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Recent studies reported elevated concentrations of ultrafine particles UFP near airports.

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Little is known about the health effects of UFP from aviation. Since UFP can deposit deep into the lungs and other organs, they may cause ificant adverse health effects. We investigated health effects of controlled short-term human exposure to UFP near a major airport.

In this study, 21 healthy non-smoking volunteers age range: 18—35 years were repeatedly 2—5 visits exposed for 5 h to ambient air near Schiphol Airport, while performing intermittent moderate exercise i. Pre- to post-exposure changes in cardiopulmonary outcomes spirometry, forced exhaled nitric oxide, electrocardiography and blood pressure were assessed and related to total- and size-specific particle concentrations PNCusing linear mixed effect models.

A 5—95th percentile increase in exposure to UFP i. Short-term exposures to aviation-related UFP near a major airport, was associated with decreased lung function mainly FVC and a prolonged QTc interval in healthy volunteers.

The effects were relatively small, however, they appeared after single exposures of 5 h in young healthy adults. As this study cannot make any inferences about long-term health impacts, appropriate studies investigating potential health effects of long-term exposure to airport-related UFP, are urgently needed.

Download PDF Download. Environment International VolumeAugust Author links open overlay panel A. Lammers a N. Janssen b A. Boere b M. Berger a C. Longo a S. Vijverberg a A. Neerincx a A. Maitland - van der Zee a F. Cassee b c.

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Abstract Background Recent studies reported elevated concentrations of ultrafine particles UFP near airports. Objective We investigated health effects of controlled short-term human exposure to UFP near a major airport. Methods In this study, 21 healthy non-smoking volunteers age range: 18—35 years were repeatedly 2—5 visits exposed for 5 h to ambient air near Schiphol Airport, while performing intermittent moderate exercise i.

Discussion Short-term exposures to aviation-related UFP near a major airport, was associated with decreased lung function mainly FVC and a prolonged QTc interval in healthy volunteers. Keywords Ultrafine particles. Recommended articles Citing articles 0.

Published by Elsevier Ltd.

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